1.
Pediatr Infect Dis J
; 43(3): e84-e86, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38091492
RESUMO
Acute necrotizing encephalopathy (ANE) is a rare childhood neurological disorder. The familiar type of ANE (ANE1) is associated with a mutation in the RANBP2 gene. Both SARS-CoV-2 and RANBP2 mutations are responsible for the manifestation of a hyper-inflammatory response that invades the central nervous system and plays a key role in the rapid progression of encephalopathy.